American restaurants in Manchester City Centre, Manchester

The American cuisine is a vibrant blend of global influences, featuring iconic burgers, savory barbecue, American pizza, buffalo wings and much more. Enjoy American food classics and innovative flavors from the United States.

  1. 1. Northern Soul Grilled Cheese

    Unit G20, 21, Smithfield Buildings, 44 Tib St, M4 1LA, Manchester City Centre/Northern Quarter
    5.0  (1 review)
    • American restaurant
    Website

  2. 2. Bunny Jackson's

    1 Jack Rosenthal St, M15 4RA, Manchester City Centre
    • Cheap bar
    Website
  3. The best American restaurants in Manchester

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  4. 3. Cane & Grain

    49, 51 Thomas St, M4 1NA, Manchester City Centre/Northern Quarter
    • Bar
    • American restaurant
    Website

  5. 4. Fat Pat's

    88 Portland St, M1 4GX, Manchester City Centre
    • American restaurant
    Website

  6. 5. Hard Rock Cafe Manchester

    The Printworks, M4 2BS, Manchester City Centre
    • American restaurant
    Website

  7. 6. Honi Poke Manchester

    1 St Ann St, M2 7LR, Manchester City Centre
    • Fast food restaurant
    • Takeaway restaurant
    • American restaurant
    Website

  8. 7. House of Hoagie

    8 Dale St, M1 1JA, Manchester City Centre/Northern Quarter
    • American restaurant
  9. The best burgers in Manchester

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  10. 8. Kong's NQ

    101, 103 Oldham St, M4 1LW, Manchester City Centre/Northern Quarter
    • Restaurant that serves street food
    • Beer bar

  11. 9. Micky's Real Nice Sandwiches NQ

    26 Lever St, M1 1DW, Manchester City Centre/Northern Quarter
    • American restaurant

  12. 10. Quarter House Beer & BBQ

    11 Stevenson Square, M1 1DB, Manchester City Centre/Northern Quarter
    • Pasta restaurant
    • Burger restaurant
    • American restaurant
    Website

  13. 11. Runyon's Restaurant

    59 Portland St, M1 3HP, Manchester City Centre
    • American restaurant
    Website

  14. 12. Slim Chickens Arndale

    Unit R8, Manchester Arndale, M4 3AQ, Manchester City Centre
    • Fast food restaurant
    • American restaurant
    Website
  15. The best lunch in Manchester city centre

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  16. 13. Street Guys

    Courtlets House, 6-7 Butter Ln, M3 2PD, Manchester City Centre
    • Burger restaurant
    • Fast food restaurant
    • American restaurant
    Website

  17. 14. The Blues Kitchen Manchester

    13 Quay St, M3 3HN, Manchester City Centre
    • American restaurant
    • Restaurant with live music
    Website

  18. 15. Yard & Coop

    37 Edge St, M4 1HW, Manchester City Centre/Northern Quarter
    • American restaurant
    Website

  19. 16. Almost Famous NQ

    49-51 Edge St, M4 1HW, Manchester City Centre/Northern Quarter
    4.0  (1 review)
    • Burger restaurant
    Website

  20. 17. Moose Coffee Piccadilly

    Piccadilly Station Approach, M1 2GH, Manchester City Centre
    3.0  (1 review)
    • Breakfast restaurant
    • Brunch restaurant
    Website
  21. The best happy hours in Manchester

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  22. 18. Archie's Manchester Arndale

    Manchester Arndale, M4 3AD, Manchester City Centre
    • Burger restaurant
    Website

  23. 19. Archie's Piccadilly

    Gateway House, Piccadilly, M1 2GH, Manchester City Centre
    • Burger restaurant
    Website

  24. 20. Archie's Takeaway

    72 Oxford St, M1 5NH, Manchester City Centre
    • Burger restaurant
    • Takeaway restaurant
    Website

  25. 21. Crabbish

    187 Chapel St, Salford, M3 5EQ, Manchester City Centre/Salford
    • Seafood restaurant

  26. 22. Detroit Slims Circle Square

    1 Circle Square, M1 7FS, Manchester City Centre
    • Pizza place
    • American restaurant
    Website
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  28. 23. Eggslut Manchester

    129 Deansgate, M3 3WR, Manchester City Centre
    • American restaurant
    • Breakfast restaurant
    Website

  29. 24. Five Guys Manchester Arndale

    Arndale Market Centre, 98 Corporation St, M4 3AJ, Manchester City Centre
    • Burger restaurant
    • Fast food restaurant
    Website

  30. 25. Five Guys Piccadilly Gardens

    17 Piccadilly, M1 1LS, Manchester City Centre/Northern Quarter
    • Burger restaurant
    • Fast food restaurant
    Website

  31. 26. Louis Manchester

    3 Hardman St, M3 3HF, Manchester City Centre/Spinningfields
    • Italian restaurant
    • Luxury restaurant
    Website

  32. 27. Manahatta

    188-192 Deansgate, M3 3ND, Manchester City Centre/Spinningfields
    • Cocktail bar
    • American restaurant
    Website
  33. The best sandwiches in Manchester

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  34. 28. Moose Coffee York Street

    York House, 20 York St, M2 2BB, Manchester City Centre
    • Breakfast restaurant
    • Brunch restaurant
    Website

  35. 29. Popeyes Manchester Piccadilly

    One Piccadilly Gardens, M1 1RG, Manchester City Centre
    • Fast food restaurant
    Website

  36. 30. Salt Dog Slim's Manchester

    17 Bow Ln, M2 4FW, Manchester City Centre
    • Cheap bar
    • Cocktail bar
    Website

  37. 31. Slap & Pickle Society Manchester

    Unit 5 - Society, 100 Barbirolli Square, M2 3BD, Manchester City Centre
    • Burger restaurant
    Website

  38. 32. Super Awesome Deluxe

    12 Thomas St, M4 1DH, Manchester City Centre/Northern Quarter
    • Burger restaurant
    Website
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  40. 33. The Pen and Pencil

    57 Hilton St, M1 2EJ, Manchester City Centre/Northern Quarter
    • American restaurant
    • Cocktail bar
    Website

  41. 34. The Shack

    69 High St, M4 1FS, Manchester City Centre/Northern Quarter
    • Burger restaurant
    • Bar
    Website
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Which are the best American restaurants in Manchester City Centre, Manchester?

We have a list of 34 American restaurants in Manchester City Centre, Manchester. The top rated ones include:

  1. Northern Soul Grilled Cheese
  2. Bunny Jackson's
  3. Cane & Grain